Dune is set on the desert planet Arrakis thousands of years into the future. The people of Arrakis have evolved advanced physical and mental abilities. The most valuable substance in the Dune universe is a spice that is only found on Arrakis. The Dune civilization is ruled by rival noble houses.
For most people, Dune is a nature name, so if you're looking for something that doesn't scream 'geek', this would work. It is unusual, and doesn't appear in the Social Security name database. I think it's more suitable for boys.
Oh, and check out this post over at Baby Name Pondering. I'm a little dubious on using Pixel for a person, but it's adorable on that cat!